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Results:: Hypogonadotropin (FSH and LH) and hyperandrogenaemia (total and free testosterone) were significantly prominent among obese girls. Correlation between gonadotropin (FSH and LH), androgen (Total Testosterone and free Testosterone) and all the studied variables for the 3 groups under study (obese, overweight, control) revealed constant relations. Gonadotropin and androgens had opposing correlations. Gonadotropin had significant negative correlations, and androgens had significant positive correlations with the anthropometric obesity markers (BMI, Waist C, and W/H ratio), HbA1c, insulin, insulin resistance and lipid profile (triglycerides, total cholesterol and LDL). In addition, Gonadotropin had significant positive correlations, and androgens had significant negativee correlations with estradiol and HDL, and insignificant correlation with age.
Conclusion: Obesity and its associated abnormalities may be the cause of infertility in obese girls. Hormonal levels are disturbed and the clinical picture gives the impression of infertility. The gonadotropin and androgen levels of women are significantly higher than those of men, and affect the female reproductive system, thereby affecting fertility. The pattern of hormonal variation is similar in both sexes, but obesity itself may exert a greater influence on the female. Further studies with larger sample size are required to assess the impact of obesity on reproduction.
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