Genomes 3 Ta Brown Pdf.44

Genomes 3 Ta Brown Pdf.44

Genomes 3 Ta Brown Pdf.44 >> https://fancli.com/2ta1PS

An example of homeotic selector genes is the vertebrate Hox gene family. Hox genes have been studied for more than 20 years in Drosophila, and the same Hox genes are present in all living animals. This clade was named the Hox gene family because the first Hox genes were discovered in a variety of Drosophila species and were designated as Antennapedia and bithorax [20, 21]. The corresponding gene clusters are called the Hox and Antennapedia gene clusters (HAC and ATC), respectively [22, 23]. The Drosophila ATC cluster contains four genes - Ubx, Abd-A, Abd-B and Abd-C. The murine homologues have the same order, but the genes are designated by the prefixes Mox, Mab, Mox2 and Mox3. Then, the human genome was scanned and it was found that the human Hox-A locus contained a dozen Hox-like genes, with nine of them corresponding to the mouse homologues. The human Hox-B locus contained 11 human Hox-like genes [24, 25]. The Hox genes have been discovered in many other chordate animals, which implies that they are ancient and highly conserved. These genes are a key part of the body plan specification process, because they determine whether a segment will be head, trunk, limb or tail [26, 27]. Several functions of the Hox genes have been identified: (a) Hox genes are involved in determining segment identity by specifying the pattern of cuticular and epidermal cell types in the developing embryo [28]; (b) the Hox 827ec27edc